OR4Q3

Protein-coding gene in the species Homo sapiens
OR4Q3
Identifiers
AliasesOR4Q3, C14orf13, HSA6, OR14-3, OR4Q4, c14_5008, olfactory receptor family 4 subfamily Q member 3
External IDsMGI: 3030569; HomoloGene: 71977; GeneCards: OR4Q3; OMA:OR4Q3 - orthologs
Gene location (Mouse)
Chromosome 14 (mouse)
Chr.Chromosome 14 (mouse)[1]
Chromosome 14 (mouse)
Genomic location for OR4Q3
Genomic location for OR4Q3
Band14|14 C1Start50,580,069 bp[1]
End50,586,329 bp[1]
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • olfactory receptor activity
  • transmembrane signaling receptor activity
  • signal transducer activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
Biological process
  • sensory perception of smell
  • detection of chemical stimulus involved in sensory perception of smell
  • detection of chemical stimulus involved in sensory perception
  • signal transduction
  • response to stimulus
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

441669

257909

Ensembl

n/a

ENSMUSG00000046210

UniProt

Q8NH05

Q7TRM4

RefSeq (mRNA)

NM_172194
NM_001405963

NM_001011754

RefSeq (protein)

NP_751944

NP_001011754

Location (UCSC)n/aChr 14: 50.58 – 50.59 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 4Q3 is a protein that in humans is encoded by the OR4Q3 gene.[4]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

  • Olfactory receptor

References

  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046210 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ a b "Entrez Gene: OR4Q3 olfactory receptor, family 4, subfamily Q, member 3".

Further reading

  • Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. Bibcode:2000PNAS...97.2870R. doi:10.1073/pnas.040580197. PMC 16022. PMID 10706615.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
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