Satoshi Ōmura

Satoshi Ōmura
大村 智
Ōmura, pada Disember 2015
Kelahiran	(1935-07-12) 12 Julai 1935 (umur 88) Nirasaki, Yamanashi, Jepun
Warganegara	Jepun
Pusat pendidikan	Universiti Yamanashi Universiti Sains Tokyo (M.S., Sc. D.)
Terkenal kerana	Avermektin dan Ivermektin Penemuan lebih daripada 480 sebatian baru
Anugerah	Hadiah Akademi Jepun (1990) Pingat Emas Koch (1997) Anugerah Kesihatan Sejagat Gairdner (2014) Hadiah Nobel dalam Fisiologi atau Perubatan (2015)
Kerjaya saintifik
Bidang	Biokimia
Institusi	Universiti Kitasato Universiti Wesleyan
Penasihat akademik	Koji Nakanishi Max Tishler

Satoshi Ōmura [satoɕi oːmu͍ɽa] (大村 智code: ja is deprecated , Ōmura Satoshi, lahir 12 Julai 1935) ialah ahli biokimia Jepun. Beliau terkenal dengan penemuan dan perkembangan pelbagai farmaseutikal yang asalnya berlaku dalam mikroorganisma.^[1] Pada 2015, beliau dianugerahkan Hadiah Nobel dalam Fisiologi atau Perubatan bersama William C. Campbell dan Tu Youyou.^[2][3][4][5]

Penerbitan

• Ōmura, S.; wai, A.; Hirano, A.; Nakagawa, A.; Awaya, J.; Tsuchiya, H.; Takahashi, Y.; Masuma, R. (1977). "A new alkaloid AM-2282 of Streptomyces origin: Fermentation, isolation and preliminary characterization". J. Antibiot. 30 (4): 275–282. doi:10.7164/antibiotics.30.275. PMID 863788.
• Burg, R. W.; Miller, B. M.; Baker, E. E.; Birnbaum, J.; Currie, S. A.; Hartman, R.; Kong, Y.-L.; Monaghan, R.; Olson, G.; Putter, I.; Tunac, J. B.; Wallick, H.; Stapley, E. O.; Oiwa, R.; Ōmura, S. (1979). "Avermectins, new family of potent anthelmintic agents: producing organism and fermentation". Antimicrob. Agents Chemother. 15 (3): 61–367. doi:10.1128/AAC.15.3.361. PMC 352666. PMID 464561.
• Hopwood, D.A.; Malphatida, F.; Kieser, H.M.; Ikeda, J.; Juncan, J.; Fujii, B.A.M.; Rudd, H.; Floss, G.; Ōmura, S. (1984). "Production of 'hybrid' antibiotics by genetic engineering". Nature. 314 (6012): 642–644. doi:10.1038/314642a0. PMC 180355. PMID 3460518.
• Ikeda, H.; Nonomiya, T.; Usami, M.; Ohta, T; Ōmura, S. (1999). "Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis". Proc. Natl. Acad. Sci. 96 (17): 9509–9514. doi:10.1073/pnas.96.17.9509. PMC 22239. PMID 10449723.
• Hayashi, M.; Rho, M.-C.; Enomoto, A.; Fukami, A.; Kim, Y.-P.; Kikuchi, Y.; Sunazuka, T.; Hirose, T.; Komiyama, K.; Ōmura, S. (2002). "Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130". Proc. Natl. Acad. Sci. 99 (21): 14728–14739. doi:10.1073/pnas.211433198. PMC 59794. PMID 11572948.
• Hirose, T.; Sunazuka, T.; Ōmura, S. (2010). "Recent development of two chitinase inhibitors, argifin and argadin, produced by soil microorganisms (Rev. article)". Proc. Jpn. Acad. 86 (2): 85–102. doi:10.2183/pjab.86.85. PMC 3417560. PMID 20154467.
• Matoba, N.; Husk, A.S.; Barnett, B.W.; Pickel, M.M.; Arntzen, C.J.; Montefiori, D.C.; Takahashi, A.; Tanno, K; Omura, Satoshi; Cao, C.; Mooney, J.P.; Hanson, C.V.; Tanaka, H. (2010). "HIV-1 Neutralization Profile and Plant-Based Recombinant Expression of Actinohivin, an Env Glycan-Specific Lectin Devoid of T-Cell Mitogenic Activity". PLoS ONE. 5 (6): e11143. doi:10.1371/journal.pone.0011143. PMC 2886112. PMID 20559567.
• Nakano, H.; Ōmura, S. (2009). "Chemical biology of natural indolocarbazole products: 30 years since the discovery of staurosporine (Review article)". J. Antibiot. 62 (1): 17–26. doi:10.1038/ja.2008.4. PMID 19132059.
• Ōmura, S. (2011). "Microbial metabolites: 45 years of wandering, wondering and discovering". Tetrahedron. 67: 6420–6459. doi:10.1016/j.tet.2011.03.117.

Rujukan

Pautan luar

• Professor Satoshi Omura
• Satoshi Ōmura | People | THE KITASATO INSTITUTE
• Nirasaki Omura Art Museum
• Satoshi Ōmura Quotes With Pictures