MRGPRX4

Protein-coding gene in the species Homo sapiens
MRGPRX4
Identifiers
AliasesMRGPRX4, GPCR, MRGX4, SNSR6, MAS related GPR family member X4
External IDsOMIM: 607230; MGI: 3033139; HomoloGene: 86184; GeneCards: MRGPRX4; OMA:MRGPRX4 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for MRGPRX4
Genomic location for MRGPRX4
Band11p15.1Start18,172,837 bp[1]
End18,174,280 bp[1]
Gene location (Mouse)
Chromosome 7 (mouse)
Chr.Chromosome 7 (mouse)[2]
Chromosome 7 (mouse)
Genomic location for MRGPRX4
Genomic location for MRGPRX4
Band7|7 B4Start47,670,719 bp[2]
End47,677,345 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • middle temporal gyrus

  • adipose tissue

  • lactiferous duct

  • temporal lobe

  • brain

  • cerebral cortex

  • spinal ganglia

  • vulva
Top expressed in
  • lip

  • neural tube
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • signal transducer activity
  • G protein-coupled receptor activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
  • integral component of plasma membrane
Biological process
  • G protein-coupled receptor signaling pathway
  • signal transduction
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

117196

404242

Ensembl

ENSG00000179817

ENSMUSG00000070552

UniProt

Q96LA9

Q8CIP3

RefSeq (mRNA)

NM_054032

NM_207540

RefSeq (protein)

NP_473373

NP_997423

Location (UCSC)Chr 11: 18.17 – 18.17 MbChr 7: 47.67 – 47.68 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mas-related G-protein coupled receptor member X4 is a protein that in humans is encoded by the MRGPRX4 gene.[5][6]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000179817 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000070552 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Dong X, Han S, Zylka MJ, Simon MI, Anderson DJ (Sep 2001). "A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons". Cell. 106 (5): 619–32. doi:10.1016/S0092-8674(01)00483-4. PMID 11551509. S2CID 14119088.
  6. ^ "Entrez Gene: MRGPRX4 MAS-related GPR, member X4".

Further reading

  • Lembo PM, Grazzini E, Groblewski T, et al. (2002). "Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs". Nat. Neurosci. 5 (3): 201–9. doi:10.1038/nn815. PMID 11850634. S2CID 42544746.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • v
  • t
  • e
Neurotransmitter
Adrenergic
Purinergic
Serotonin
Other
Metabolites and
signaling molecules
Eicosanoid
Other
Peptide
Neuropeptide
Other
Miscellaneous
Taste, bitter
Orphan
Other
Adhesion
Orphan
Other
Taste, sweet
Other
Class F: Frizzled & Smoothened
Frizzled
Smoothened
Stub icon

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e