Lasalocid

Chemical compound
  • QP51BB02 (WHO)
Identifiers
  • 6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-
CAS Number
  • 25999-31-9 ☒N
PubChem CID
  • 5360807
ChemSpider
  • 4514598 checkY
UNII
  • W7V2ZZ2FWB
KEGG
  • D04671 checkY
ChEBI
  • CHEBI:92181
ChEMBL
  • ChEMBL145347 checkY
CompTox Dashboard (EPA)
  • DTXSID9048485 Edit this at Wikidata
ECHA InfoCard100.043.077 Edit this at WikidataChemical and physical dataFormulaC34H54O8Molar mass590.798 g·mol−13D model (JSmol)
  • Interactive image
  • O=C(O)c1c(O)c(ccc1CC[C@@H](C)[C@H](O)[C@@H](C(=O)[C@@H]([C@H]3O[C@@]([C@@H]2O[C@H]([C@](O)(CC2)CC)C)(CC)C[C@@H]3C)CC)C)C
InChI
  • InChI=1S/C34H54O8/c1-9-25(31-21(6)18-34(11-3,42-31)26-16-17-33(40,10-2)23(8)41-26)30(37)22(7)28(35)19(4)12-14-24-15-13-20(5)29(36)27(24)32(38)39/h13,15,19,21-23,25-26,28,31,35-36,40H,9-12,14,16-18H2,1-8H3,(H,38,39)/t19-,21+,22+,23+,25+,26-,28+,31+,33-,34+/m1/s1 checkY
  • Key:BBMULGJBVDDDNI-OWKLGTHSSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Lasalocid is an antibacterial agent and a coccidiostat, which is produced by strains of Streptomyces lasaliensis. It is the drug in the feed additives called Bovatec and Avatec.[1]

Lasalocid is able to make neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can also transport big organic cations like dopamine.[citation needed]

Horses and dogs[2] are very susceptible to the toxic effects of lasalocid, and it should never be administered to non-target species.

References

  1. ^ FOIA Drug Summaries.
  2. ^ BMJ Veterinary Record
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Xenobiotic-sensing receptor modulators
CARTooltip Constitutive androstane receptorPXRTooltip Pregnane X receptor
See also
Receptor/signaling modulators


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