Inositol nicotinate

Chemical compound
  • C04AC03 (WHO)
Legal statusLegal status
  • US: OTC
Identifiers
  • cyclohexane-1,2,3,4,5,6-hexayl hexanicotinate
CAS Number
  • 6556-11-2
PubChem CID
  • 3720
ChemSpider
  • 16736141
UNII
  • A99MK953KZ
KEGG
  • D01813
CompTox Dashboard (EPA)
  • DTXSID2023147 Edit this at Wikidata
ECHA InfoCard100.026.806 Edit this at WikidataChemical and physical dataFormulaC42H30N6O12Molar mass810.732 g·mol−13D model (JSmol)
  • Interactive image
Melting point255 °C (491 °F)
  • O=C(O[C@H]6[C@H](OC(=O)c1cccnc1)[C@H](OC(=O)c2cccnc2)[C@H](OC(=O)c3cccnc3)[C@@H](OC(=O)c4cccnc4)[C@@H]6OC(=O)c5cccnc5)c7cccnc7

Inositol nicotinate, also called inositol hexanicotinate and inositol hexaniacinate, is marketed in the United States as a "no-flush niacin" dietary supplement.[1] Flushing, in physiology, essentially means that epidermal tissues have become reddened, such as when the skin is irritated from the histamine responses related to an allergic reaction, or from recent physical exercise, or even from anger or embarrassment.

This form of niacin is supposed to reduce or prevent flushing by being broken down into the metabolites niacin (nicotinic acid) and inositol at a slow rate.[1]

See also

References

  1. ^ a b Taheri R (15 January 2003). "No-Flush Niacin for the Treatment of Hyperlipidemia". Medscape.com. Retrieved 14 September 2010.


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