Descinolone acetonide

Chemical compound
Descinolone acetonide
Clinical data
Other namesCL-27071; Desoxytriamcinolone acetonide; 21-Desoxytriamcinoline acetonide; 9α-Fluoro-11β,16α,17α-trihydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; 9α-Fluoro-11β-hydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-6b-Acetyl-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
CAS Number
  • 2135-14-0
PubChem CID
  • 11954034
ChemSpider
  • 10128329
UNII
  • ENR9Z582HW
KEGG
  • D03691
ChEBI
  • CHEBI:34672
ChEMBL
  • ChEMBL2106177
CompTox Dashboard (EPA)
  • DTXSID60943909 Edit this at Wikidata
ECHA InfoCard100.016.699 Edit this at Wikidata
Chemical and physical data
FormulaC24H31FO5
Molar mass418.505 g·mol−1
3D model (JSmol)
  • Interactive image
  • CC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@]4([C@H]3CCC5=CC(=O)C=C[C@@]54C)F)O)C)OC(O2)(C)C
InChI
  • InChI=1S/C24H31FO5/c1-13(26)24-19(29-20(2,3)30-24)11-17-16-7-6-14-10-15(27)8-9-21(14,4)23(16,25)18(28)12-22(17,24)5/h8-10,16-19,28H,6-7,11-12H2,1-5H3/t16-,17-,18-,19+,21-,22-,23-,24+/m0/s1
  • Key:BSHYASCHOGHGHW-PIQRJGQMSA-N

Descinolone acetonide (developmental code name CL-27071), also known as desoxytriamcinolone acetonide, is a synthetic glucocorticoid corticosteroid which was never marketed.[1]

References

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 362–. ISBN 978-1-4757-2085-3.


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GRTooltip Glucocorticoid receptor
Agonists
  • Nonsteroidal glucocorticoids: AZD-5423
  • GSK-9027
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
  • Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids
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