Antithrombotic

Drug that reduces the formation of blood clots

An antithrombotic agent is a drug that reduces the formation of blood clots (thrombi).[1][2] Antithrombotics can be used therapeutically for prevention (primary prevention, secondary prevention) or treatment of a dangerous blood clot (acute thrombus). In the U.S., the American College of Chest Physicians publishes clinical guidelines for clinicians for the use of these drugs to treat and prevent a variety of diseases.[citation needed]

Processes

Different antithrombotics affect different blood clotting processes:

  • Antiplatelet drugs limit the migration or aggregation of platelets.
  • Anticoagulants limit the ability of the blood to clot.
  • Thrombolytic drugs act to dissolve clots after they have formed.

See also

  • Direct Xa inhibitor
  • Warfarin

References

  1. ^ "Antithrombotics" at Dorland's Medical Dictionary
  2. ^ http://cancerweb.ncl.ac.uk/cgi-bin/omd?antithrombotic [dead link]

External links

  • Antithrombotic Therapy / American Society of Hematology
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Major chemical drug groups – based upon the Anatomical Therapeutic Chemical Classification System
gastrointestinal tract
/ metabolism (A)
blood and blood
forming organs (B)cardiovascular
system (C)skin (D)genitourinary
system (G)endocrine
system (H)infections and
infestations (J, P, QI)malignant disease
(L01–L02)immune disease
(L03–L04)muscles, bones,
and joints (M)brain and
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system (R)sensory organs (S)other ATC (V)
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Antiplatelet drugs
Glycoprotein IIb/IIIa inhibitors
ADP receptor/P2Y12 inhibitors
Prostaglandin analogue (PGI2)
COX inhibitors
Thromboxane inhibitors
Phosphodiesterase inhibitors
Other
Anticoagulants
Vitamin K antagonists
(inhibit II, VII, IX, X)
Factor Xa inhibitors
(with some II inhibition)
Heparin group/
glycosaminoglycans/
(bind antithrombin)
Direct Xa inhibitors ("xabans")
Direct thrombin (IIa) inhibitors
Other
Thrombolytic drugs/
fibrinolytics
Non-medicinal


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