Androgen-dependent tfpi-regulating protein

Protein-coding gene in the species Homo sapiens
ADTRP
Identifiers
AliasesADTRP, AIG1L, C6orf105, dJ413H6.1, androgen dependent TFPI regulating protein
External IDsOMIM: 614348; MGI: 1924596; HomoloGene: 13107; GeneCards: ADTRP; OMA:ADTRP - orthologs
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for ADTRP
Genomic location for ADTRP
Band6p24.1Start11,712,054 bp[1]
End11,807,046 bp[1]
Gene location (Mouse)
Chromosome 13 (mouse)
Chr.Chromosome 13 (mouse)[2]
Chromosome 13 (mouse)
Genomic location for ADTRP
Genomic location for ADTRP
Band13|13 A4Start41,916,624 bp[2]
End42,001,160 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sperm

  • mucosa of transverse colon

  • jejunal mucosa

  • retinal pigment epithelium

  • rectum

  • mucosa of sigmoid colon

  • skin of thigh

  • mucosa of ileum

  • duodenum

  • seminal vesicula
Top expressed in
  • left lobe of liver

  • right kidney

  • duodenum

  • spermatid

  • human kidney

  • morula

  • jejunum

  • esophagus

  • lip

  • ileum
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • hydrolase activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • endomembrane system
  • caveola
  • cell surface
  • membrane
  • intracellular anatomical structure
Biological process
  • positive regulation of gene expression
  • negative regulation of blood coagulation
  • long-chain fatty acid catabolic process
  • cellular response to steroid hormone stimulus
  • positive regulation of protein phosphorylation
  • cell migration involved in sprouting angiogenesis
  • negative regulation of leukocyte migration
  • negative regulation of extracellular matrix constituent secretion
  • protein kinase B signaling
  • negative regulation of protein secretion
  • cellular response to oxidised low-density lipoprotein particle stimulus
  • negative regulation of leukocyte cell-cell adhesion
  • negative regulation of lymphocyte migration
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

84830

109254

Ensembl

ENSG00000111863

ENSMUSG00000058022

UniProt

Q96IZ2

Q8C138

RefSeq (mRNA)

NM_001143948
NM_032744

NM_001145875
NM_175417

RefSeq (protein)

NP_001137420
NP_116133

NP_001139347
NP_780626

Location (UCSC)Chr 6: 11.71 – 11.81 MbChr 13: 41.92 – 42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Androgen-dependent TFPI-regulating protein is a protein in humans that is encoded by the ADTRP gene. [5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000111863 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000058022 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Androgen-dependent TFPI-regulating protein". Retrieved 2013-02-07.

Further reading


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