All-trans-retinyl ester 13-cis isomerohydrolase

all-trans-Retinyl ester 13-cis isomerohydrolase
Identifiers
EC no.3.1.1.90
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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The enzyme all-trans-retinyl ester 13-cis isomerohydrolase (EC 3.1.1.90; systematic name all-trans-retinyl ester acylhydrolase, 13-cis retinol forming[1] catalyses the reaction

an all-trans-retinyl ester + H2O {\displaystyle \rightleftharpoons } 13-cis-retinol + a fatty acid

References

  1. ^ Takahashi Y, Moiseyev G, Chen Y, Farjo K, Nikolaeva O, Ma JX (April 2011). "An enzymatic mechanism for generating the precursor of endogenous 13-cis retinoic acid in the brain". The FEBS Journal. 278 (6): 973–87. doi:10.1111/j.1742-4658.2011.08019.x. PMC 3073448. PMID 21235714.

External links

  • All-trans-retinyl+ester+13-cis+isomerohydrolase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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Hydrolase: esterases (EC 3.1)
3.1.1: Carboxylic
ester hydrolases3.1.2: Thioesterase3.1.3: Phosphatase3.1.4:
Phosphodiesterase3.1.6: SulfataseNuclease (includes
deoxyribonuclease
and ribonuclease)
3.1.11-16:
Exonuclease
Exodeoxyribonuclease
Exoribonuclease
3.1.21-31:
Endonuclease
Endodeoxyribonuclease
Endoribonuclease
either deoxy- or ribo-    
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